Abstract
Accurate early diagnosis is the most important single factor in the case of the patient with appendicitis. When the clinical findings are not diagnostic, a barium enema study may demonstrate changes in the caecum and the appendix diagnostic of the disease. A series of 40 barium enema studies was performed in patients suspected of suffering from appendicitis or in order to rule out appendiceal disease when the clinical signs and findings were not conclusive. A reliable sign was found to be a reversed 3 filling defect of the caecum due to oedema of the caecal wall and mesentry. It is believed that this diagnostic sign of appendicitis has not been previously described and that it is very helpful in the differential diagnosis of the acute abdomen.
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