Abstract
Background Acute chronic obstructive pulmonary disease (COPD) exacerbation is a serious condition with a mortality of 10%, and the condition often require treatment with antibiotics. The aims of the study were 1) to evaluate which antibiotics, the physicians prescribe in first line treatment to patients with acute COPD exacerbation, and 2) to compare the given treatments with national guidelines.
Highlights
Acute chronic obstructive pulmonary disease (COPD) exacerbation is a serious condition with a mortality of 10%, and the condition often require treatment with antibiotics.The aims of the study were 1) to evaluate which antibiotics, the physicians prescribe in first line treatment to patients with acute COPD exacerbation, and 2) to compare the given treatments with national guidelines.Oral antibiotics were used in 17% of the patients
The use of antibiotics in treatment of acute COPD exacerbations does not adhere to national guidelines
Cefuroxime was the most commonly used antibiotic in the treatment of acute COPD exacerbation
Summary
Acute chronic obstructive pulmonary disease (COPD) exacerbation is a serious condition with a mortality of 10%, and the condition often require treatment with antibiotics.The aims of the study were 1) to evaluate which antibiotics, the physicians prescribe in first line treatment to patients with acute COPD exacerbation, and 2) to compare the given treatments with national guidelines.Oral antibiotics were used in 17% of the patients. Acute chronic obstructive pulmonary disease (COPD) exacerbation is a serious condition with a mortality of 10%, and the condition often require treatment with antibiotics. The aims of the study were 1) to evaluate which antibiotics, the physicians prescribe in first line treatment to patients with acute COPD exacerbation, and 2) to compare the given treatments with national guidelines. Oral antibiotics were used in 17% of the patients. 88% were treated with amoxicillin in combination with clavulanic acid and 12% with phenoxymethylpenicillin. One patient was treated with cefuroxime in combination with oral azithromycin. The national guidelines recommend cefuroxime as first choice drug in hospital treatment of acute COPD exacerbation
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