Abstract
Transferrin is a glycoprotein universally described as a carrier in the iron cycle between the organic deposits (ferritin and hemosiderin) and the sites responsible for hematopoiesis (bone marrow). An in-depth analysis of the structure and function of transferrin, has allowed us to predict an unsuspected non-canonical function of this protein . In this work we propose an energy landscape theory based on a free-scale macro-molecular simulation of the role of transferrin in the metabolism of mature red blood cells.
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