Abstract

Tinidazole is a drug of choice for many aerobic or anaerobic bacterial infections. But, its adverse reactions affect almost all body systems. Several studies of tinidazole were reviewed which suggests that use of tinidazole leads to hypersensitivity or anaphylactic reactions, fixed drug eruptions, rash, erythema, Stevens Johnson Syndrome etc. Again, the rationality of fixed dose combination of tinidazole is controversial. It is a widely debated issue in clinical practice of India. So, alertness of both, the patient and the physician is important towards promoting safe and rational use of tinidazole. Also, drug regulatory bodies should take urgent action to mitigate the rampant use of irrational fixed dose combinations of tinidazole.

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