Abstract
Van Slyke and Hiller1 reported evidence that the phosphotungstate precipitate obtained from hydrolyzed gelatin contained amino acid material other than the hexone bases usually found in this precipitate. Other problems prevented continuance of work on the isolation of the material. It was taken up by Van Slyke and Robson2 but after preparation of a copper salt, since found to be contaminated with proline, the work was again discontinued by Robson's return to England.The unidentified base has now been isolated and recrystallized, both as the picrate and as the hydrochloride, and has the composition of a hydroxylysine. After removal of arginine and histidine as silver salts the residual “lysine fraction” is freed of adherent mono-amino acids by repeated precipitation in very dilute solution as phosphotungstate. The greater part of the lysine is removed by addition of enough picric acid to the hot aqueous solution to combine with 3/4 of the amino nitrogen present. To the mother liquors enough more picric aci...
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