Abstract
The unbalance of adiponectin oligomers, RvE1 and chemerin levels are associate with increase of adiposopathy status and insulin resistance in obesity
Highlights
Obesity is characterizing by high storage and irregular distribution of white adipose tissue (WAT)
It has dysmetabolic and subclinical inflammatory process with increase synthesis of adipokines and chemokines, these processes develop into an adiposopathy status that causes insulin resistance (IR) [1,2,3,4]
Madrigal-Ruiz PM (2019) The unbalance of adiponectin oligomers, RvE1 and chemerin levels are associate with increase of adiposopathy status and insulin resistance in obesity themselves or surrounded cells to further produce inflammatory mediators [5,6]
Summary
Obesity is characterizing by high storage and irregular distribution of white adipose tissue (WAT) It has dysmetabolic and subclinical inflammatory process with increase synthesis of adipokines and chemokines, these processes develop into an adiposopathy status (pathological function of WAT) that causes insulin resistance (IR) [1,2,3,4]. Adiponectin is synthetized by WAT and suffers posttranscriptional changes, on three oligomeric forms: trimer (LMW), hexamer (MMW), and high (HMW) molecular weight. These variations display functional differences according on their levels and exert distinct biological effects and tissue-selective functions [13,14,15]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
