Abstract
1. 1. It was found that the activity of pepsin was not completely lost by surface-denaturation. 2. 2. The action of U.V. on pepsin was studied spectroscopically and it was found that there were many similarities between this action and that of tyrosinase. 3. 3. Spectroscopic and paper-chromatographic evidence was obtained for the formation of Dopa groups in solutions of pepsin by U.V. irradiation. 4. 4. The inactivation of pepsin by U.V. is probably due to the formation of Dopa from tyrosine.
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