The ultra-structural organization of the elastic network in the intra- and inter-lamellar matrix of the intervertebral disc.

Abstract

Visualization of the intra-lamellar matrix under high magnification revealed a dense network of elastic fibers that has not been previously described. The present study used extracellular matrix partial digestion to address significant gaps in understanding of disc microstructure and will contribute to multidisciplinary ultrastructure-function studies.