Abstract
For the past 15 years, the UCSC Genome Browser (http://genome.ucsc.edu/) has served the international research community by offering an integrated platform for viewing and analyzing information from a large database of genome assemblies and their associated annotations. The UCSC Genome Browser has been under continuous development since its inception with new data sets and software features added frequently. Some release highlights of this year include new and updated genome browsers for various assemblies, including bonobo and zebrafish; new gene annotation sets; improvements to track and assembly hub support; and a new interactive tool, the “Data Integrator”, for intersecting data from multiple tracks. We have greatly expanded the data sets available on the most recent human assembly, hg38/GRCh38, to include updated gene prediction sets from GENCODE, more phenotype- and disease-associated variants from ClinVar and ClinGen, more genomic regulatory data, and a new multiple genome alignment.
Highlights
The UCSC Genome Browser [1] was first released in 2001 as a tool to display the newly assembled human genome
Tool updates are improvements that allow the display of new types of data or permit users to perform new types of analysis
Software updates to the UCSC Genome Browser in previous years have included tools like the Genome Browser in a Box (GBiB) [40] and the Variant Annotation Integrator (VAI) [41]
Summary
The UCSC Genome Browser [1] was first released in 2001 as a tool to display the newly assembled human genome. Clicking on a gene in this track allows a user to explore the interaction data for that gene in a new graph visualization tool. Last year seven new hubs were added to this public listing, including three assembly hubs with genomes that are not natively displayed on the Browser.
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