Abstract
A rough parallelism exists in physostigmine poisoned rats between the clinical symptoms and the activity of the true cholinesterase of the brains. This is demonstrated by the following experimental results: 1. 1. The true-chE activity of the brains of physostigmine poisoned rats is significantly decreased compared with that of normal rats. 2. 2. The true-chE activity in the brains of rats clinically recovered from a physostigmine poisoning is significantly higher than that of rats still showing symptoms, but yet significantly lower than that of normal animals.
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