Abstract
Two amphiphilic porphyrins terminated with carboxyl were studied in AOT/ iso-octane/water reverse micelles, intending to mimic the relationship between microenvironments in organism and the amphiphilic properties of porphyrins for photodynamic therapy (PDT) drugs. The quenching of porphyrins by methyl viologen chloride and the laser flash photolysis experiments show that the longer side-chain length would promote the firm embedding of porphyrin molecules in the interfacial region of reverse micelles. Such an embedding may shift porphyrins from aggregated to monomeric form in reverse micelles and, accordingly, the slower excited state decay may increase the efficiency of the photosensitizer in PDT. The effect of amphiphilic properties on the status of porphyrins in microenvironments provides a light on the synthesis of other amphiphilic porphyrins for PDT drugs.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Photochemistry & Photobiology, A: Chemistry
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
