Abstract
Trichomoniasis is the most common curable sexually transmitted infection in the United States with around 3.7 million infections annually and is caused by the protozoa parasite Trichomonas vaginalis. The majority of those infected are asymptomatic, however, symptoms can include vaginal discharge, malodor, pruritus, and dysuria. Infection has been associated with a two-to-three-fold increased rate of HIV acquisition and is associated with preterm labor and low birth weights in pregnancy. Culture is the gold standard method for diagnosis though nucleic acid amplification tests (NAAT) have come into favor due to their high sensitivity and higher rates of detecting infection compared to wet-mount microscopy. The standard of care for treatment is 2g of metronidazole or 2g of tinidazole orally in a single dose. Alternative oral options include Metronidazole 500mg twice daily for a seven-day course. Studies have shown that metronidazole and tinidazole regimens result in cure rates of approximately 84-94% and 92-100%, respectively.
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