Abstract
TYPHOID IMMUNITY One year ago, before another Section of this Association, 1 I presented the results of a study of typhoid immunity and anti-typhoid inoculation. It was shown at that time that the factors of acquired immunity in typhoid were largely concerned with the process of phagocytosis, and those antibacterial elements which make phagocytosis possible; i. e. , the opsonins and stimulins. The other antibacterial elements, the bacteriolysins, bactericidins and agglutinins, while possessed of certain powers antagonistic to the infection during and immediately subsequent to the attack, were considered, according to work so far done, of lesser value in the perpetuation of such immunity. In this disease, as in many others accompanied by leukopenia, the problem of active immunization seems to resolve itself into a study of these measures which primarily augment the number of leukocytes, with secondary augmentation of those antitropic substances which render the leukocytes capable of phagocytosis. After
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