Abstract

The treatment of tuberculosis (TB) in children and adults has remained unchanged for more than 30 years and although new drugs are at last entering clinical trials it will be 5 - 10 years before their precise place in therapy is established. It is therefore necessary to continue to use our current drugs with care and prudence and be particularly careful about preventing the further development of drug resistance. The principles of treatment in adults and children are the same but there is an increasing appreciation that the spectrum of disease seen in childhood is different and that children also differ from adults with regard to the pharmacokinetics of drugs. (excerpt)

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