Abstract

In using the term sepsis in scarlet fever I desire to be understood as referring to a set of clinical symptoms occurring forty-eight hours or longer after the onset of the disease, which are apparently due to the invasion of the body by organisms of the streptococcus group, which, up to the present time, are not known to possess any cultural or other characteristics which serve to distinguish them from streptococci isolated from a number of other morbid conditions. The symptoms may be briefly stated as follows: No fall of temperature, or a renewed rise; abnormal swelling of the mucous membrane of the throat, with or without superficial sloughing; profuse nasal discharge; marked cervical adenitis; rapid, often irregular pulse; mental apathy; active or low delirium. Streptococci may or may not be found in the blood, and it should be said that while they are usually present in prolonged cases especially,

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