Abstract
Demecolcine (Ciba), known in England as Colcemid, has, like colchicine, the power to inhibit mitosis at the metaphase stage; it does not, like urethane, intervene at all phases of cell-division. It has proved itself to be the most specific and the least toxic of the chemotherapeutic agents available for the treatment of chronic myeloid leukaemia.
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