Abstract

Meningitis due to H. influenzae is relatively common in children. Excluding tuberculous meningitis, it is the commonest cause of meningitis in children under 2 years of age. The average age in this series of 108 patients was 2.14 years. The treatment of this type of meningitis with specific serum and human complement intrathecally, intravenous serum, with adequate supportive treatment consisting of transfusions, fluids, and vitamins, has reduced the mortality percentage from 97 to 83. By adding sulfanilamide and sulfapyridine to the above, the mortality for thirteen cases has been further reduced to 54 per cent. Meningitis due to H. influenzae is relatively common in children. Excluding tuberculous meningitis, it is the commonest cause of meningitis in children under 2 years of age. The average age in this series of 108 patients was 2.14 years. The treatment of this type of meningitis with specific serum and human complement intrathecally, intravenous serum, with adequate supportive treatment consisting of transfusions, fluids, and vitamins, has reduced the mortality percentage from 97 to 83. By adding sulfanilamide and sulfapyridine to the above, the mortality for thirteen cases has been further reduced to 54 per cent.

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