Abstract
Thyroid produces multiple essential hormones for vital life processes. Thyroid cancer has no symptoms and may be detected by ultrasound imaging incidentally for other medical conditions. An accurate computational detection model may help the precise diagnose of thyroid papillary cancer (TPC). A standard protocol captures at least the transverse and longitudinal ultrasonograms of the thyroid. This study investigated the detection problem of thyroid cancer using the ultrasound images. Our data suggested that the original local binary pattern (LBP) features extracted from the ultrasonograms were very sparse and the compressed LBP features outperformed the original version. And the best model (Acc = 0.9829) was achieved by the fivefold cross validation of the classifier support vector machine (SVM). Other sources of biomedical data may be integrated to further improve the TPC detection model in future studies.
Highlights
Thyroid is an endocrine gland at the throat and produces several important hormones using the mineral iodine [1]
This study demonstrated that the transverse ultrasonogram of the thyroid has a prediction accuracy of thyroid papillary carcinoma constantly higher than the longitudinal ultrasonogram
The transverse and longitudinal ultrasonograms of the thyroid were collected for each patient
Summary
Thyroid is an endocrine gland at the throat and produces several important hormones using the mineral iodine [1]. Thyroid cancer accounts for no more than 5% of diagnosed cancer cases in the United States and has a low mortality rate [6]. Two major subtypes of thyroid cancers, i.e., papillary and follicular cancers, have 10-year survival rates of as high as 99% and 95%, respectively [6]. Ultrasound imaging is one of the major technologies to screen the thyroid cancer at the early stage [8]. The advance of screening technology increased the incidence rate of thyroid cancers in the U.S and U.K., but the mortality remained constant or even decreased slightly [7], [9]. Thyroid cancers usually have no symptoms and are most incidentally found by the ultrasound imaging examination of other medical conditions [10].
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