Abstract

BeSO 4 injected i.v. into rats is transported in the plasma in two forms. These have been studied, using 7Be as a tracer, by ultracentrifugation, gel filtration and ion exchange chromatography techniques. Some of the rats were also given 32P. It was found that, while a small part of the dose remained of small molecular size, most of the BeSU 4 was converted to aggregates of beryllium phosphate. These aggregates were bound to plasma globulin, most probably a-globulin. The molecular proportions of these aggregates could not be determined.

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