Abstract
The transient receptor potential cation channel subfamily V member 6 (TRPV6) gene and cDNA were identified 15 years ago and exceptional observations on TrpV6 proteins and their function as a Ca(2+)-selective cation channel have been made since then. In this review we will summarize recent studies regarding the genetics, biochemical properties, and physiological functions of murine and human TrpV6 channel proteins. We will focus on TRPV6 gene polymorphisms, the start of TRPV6 translation at a non-AUG codon and the functions of TRPV6 in intestinal Ca(2+) uptake, sperm maturation, and male fertility.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
