Abstract
Guinea pigs studies have shown a correlation between the slope of the function relating psychophysical detection thresholds to pulse rate (known as multipulse integration) and the spiral ganglion cell density in electrical stimulation. If this relationship holds true in human subjects with cochlear implants, we hypothesize that multipulse integration should reduce (i.e., become shallow sloped) at stimulation sites with sharp tuning or when electrode configuration changes from broad (monopolar) to focused stimulation (bipolar). Multipulse integration was measured at all stimulation sites using two pulse rates with phase duration of 75 us in a monopolar stimulation mode (MP1 + 2) and bipolar stimulation mode (BP + 0). At selected stimulation sites, a psychophysical spatial tuning curve was also measured using a forward-masking paradigm. The multipulse integration slopes were steeper with MP electrode configuration than with BP. In MP mode, the multipulse integration slopes were steeper at stimulation sites ...
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