The Toxic Effects of Polybrominated Diphenyl Ethers on Rotifer <i>Branchionus plicatilis</i>

Abstract

In the current study, two of the most environmentally relevant Polybrominated diphenyl ethers (PBDEs) were individually evaluated for toxic effects on rotifer Brachionus plicatilis. The results showed that the life span declined significantly in all treatment groups (0.05mg/L, 0.1mg/L, 0.2mg/L BDE-47 and BDE-209) compared to the control, and BDE-47 caused significant decrease compared to BDE-209 at 0.2mg/L treatment group. Significant increases of intracellular levels of reactive oxygen species (ROS) occurred in all treatment groups except for 0.05mg/L BDE-209 treatment group compared to the control, and significant increases were observed in all BDE-47 treatment groups compared to the equivalent treatment groups of BDE-209. Meanwhile significant increases of intracellular calcium levels ([Ca2+]in) occurred in 0.1mg/L, 0.2mg/L BDE-47 and 0.2mg/L BDE-209 treatment groups compared to the control, and BDE-47 cause significant increase compared to BDE-209 at 0.2mg/L treatment group. The present study demonstrated that life span, ROS and Ca2+ were involved in PBDEs toxic effects, and toxicities of BDE-47 were higher than BDE-209. Otherwise, the toxic effects in both BDE-47 and BDE-209 were similar, which suggest that the toxic effects of two PBDEs congeners may be caused by the same toxic mechanism of action.