Abstract

A study was made of the extrinsic bacteriostatic value of different lots of two brands of several tri-phenyl methane dyes. Staphylococcus aureus Rosenbach and Bacterium communior Holland were chosen as the test organisms. The conclusions are as follows: (1) Recent lots of the two brands of each dye possess practically the same bacteriostatic value; (2) the ethyl group in brilliant green appears to be responsible for the marked inhibition of the colon organism by this dye; (3) the bacteriostatic action of a dye is influenced by the H-ion concentration and constituents of the medium and by the amount of the inoculum; (4) the therapeutic value of a dye cannot be judged by tests in vitro.

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