Abstract
The occurrence of human rabies in Indonesia approximately amounted to 168 cases. The countermeasures taken were vaccination, quick treatment for individuals, KIE (Komunikasi, Informasi, dan Edukasi; Communication, Information, and Education), surveillance, selective dog elimination and post-exposure management. Vaccination was one of the effective countermeasures against the distribution of rabies. It might be conducted either before or after the virus exposure. Despite its effectiveness, it could end in failure due to several factors, one of which was the nutritional status of patient. However, the failure could be overcome by enhancing the immune system (immunostimulator) with the administration of wild horse milk. The milk contained lactoferrin known as protein inducing antibody. Sample consisted of 15 rabbits. They were divided into three groups. Each group consisted of five rabbits. Group t1 for titer testing in immunoglobulin after anti-rabies vaccination; while Group t2 and t0 for titer testing in immunoglobulin after rabies-vaccination and administration of wild horse milk and for the control group without any treatment respectively. The results showed a titer increase in Ig G after vaccination by 40% in Group t2 and t2 (p>0.05). Besides, the administration of wild horse milk could increase titer in IgG after vaccination for two weeks (p<0.05). In Conclusion, Administration of wild horse milk could increase titer in IgG after vaccination.
Highlights
Rabies is caused by the rabies virus, a virus species of Lyssavirus genus in the family Rhabdoviridae
Stage 5 : administration of wild horse milk in the group administered with rabies vaccine
Rabies vaccine was administered to the rabbits in a subcutaneous way
Summary
Rabies is caused by the rabies virus, a virus species of Lyssavirus genus in the family Rhabdoviridae. Vaccination is an effective countermeasure against the spread of rabies It may be administered either before or after the virus exposure. The milk contains lactobacillus and destroys bacteria cells, enhances immune responses (increasing the IgA and IgG production) and activates macrophage and specific antibody response against foreign antigens (Faisal et al, 2010; Reni et al, 2010). The administration of Sumbawa wild horse milk, according to some research in vivo, can enhance immunity in Hepatitis A vaccine given to Balb/c mice. It indicates that the milk can increase receptor capacity of macrophage and cytokine production that activates macrophage. It aims to investigate the variation of immune response given by experimental animals administered with anti-rabies vaccine
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