Abstract
In their study in The Lancet Respiratory Medicine, Scott Pallett and colleagues1 assessed the performance of lateral flow serological assays and estimated the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to be 10·6% (95% CI 7·6–13·6) in asymptomatic health-care workers and 44·7% (42·0–47·4) in symptomatic health-care workers at two hospitals in London, UK. This work raises important issues in the design of seroprevalence surveys, how they should be done, and, importantly, how to interpret and act on the results.
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