Abstract
Purpose: Peripheral and central sensitization are suggested the two underlying mechanisms of pain in knee osteoarthritis (KOA). Amongst several testing procedures, pressure pain threshold (PPT) measurement is the most sensitive method for investigating the magnitude of peripheral and central sensitization in KOA. While local PPT measurement refers to peripheral sensitization, distant PPT measurement implies central sensitization. The immediate effectiveness of not end-range Maitland mobilization on alleviation of pain perception has been previously confirmed in KOA.
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