The Time Course of Disinhibition of Visual Cortex Neurons and Sensitivity to Cross-Shaped Figures

Abstract

The relationship between the responses of 74 neurons in field 17 of the cat cortex to presentation of cross-shaped figures flashing in their receptive fields and the asynchronicity with which the lines of the figures were presented were investigated. The cross sensitivity of neurons was studied with simultaneous, leading, and delayed activation of the disinhibitory zone of the receptive field in relation to the time at which its major excitatory and end-stopping inhibitory zones were stimulated. Two types of temporal interaction were identified between the receptive field zones determining cross sensitivity. In cells of the first type (14 of 23 cells), the response was maximal in conditions of simultaneous stimulation of the major and disinhibitory zones of the receptive field; neurons of the second type (nine of 23 cells) showed the opposite temporal relationship. Digital simulation showed that cross sensitivity in neurons of the first type was supported by disinhibition of end-stopping inhibition, while in neurons of the second type it depended on a combination of disinhibitory and convergence mechanisms.