Abstract
Toward the end of the nineteenth century, much interest was manifested in the study of a pathologic syndrome termed family periodic paralysis. Admirable reviews of the disease were written by Singer and Goodbody 1 and by Taylor. 2 Other notable contributions were made by Goldflam, 3 Oppenheim, 4 Mitchell, 5 Westphal 6 and others. It was not, however, until the ingenious experiments of Shinosaki 7 that any recent notable advances were made. In his summary paper of 1926, the relationship of family periodic paralysis to disturbances in the functions of the glands of internal secretion is stressed on the basis of numerous experiments. Heretofore, many other factors were considered in an attempt to elucidate the pathogenesis of periodic paralysis. Such theories, which considered malaria, scarlet fever, auto-intoxication, heredity, physical overexertion, indiscretions in diet, emotions and even internal secretory disturbances as important etiologic factors, were never adequately supported by substantial and
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
