Abstract
The preponderance of experimental data on specific dynamic action of food in thyroid diseases, reported during the last decade by six investigators from as many laboratories, indicates that there is no change from the normal (DuBois,1 Aub and Means,2 Undeutsch,3 Rolly,4 Plaut,5 and Liebesny.6) Weiss and Adler,7 however, found an increased specific dynamic action in one case of Graves' disease, while in one case of myxedema it was also increased.One never finds surviving cases of myxedema in infants or adults without active thyroid tissue. In Graves' disease thyroid activity while usually greater than normal, may be normal or subnormal. Since clinical conditions obtaining in thyroid diseases are so complex and variable, it seemed worth while to study the relation of thyroid to specific dynamic action of food under conditions more simplified and limited.If the thyroid, and hence probably its secretion, were necessary for specific dynamic action to manifest itself then no specific dynamic action should resul...
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