Abstract
The limited literature comparing testicular vs. ejaculated sperm for assisted reproduction technology (ART) is rife with heterogenous results. While a meta-analysis found that testicular sperm was superior to ejaculated sperm with respect to embryo quality and pregnancy rates, a well-designed recent study concluded that intracytoplasmic sperm injection (ICSI) outcomes with the use of Testicular Sperm Extraction (TESE) samples compared with ejaculated sperm were equivalent (1). Moreover, studies comparing Zymot™, a microfluidic sperm separation device vs standard density gradient centrifugation (DGC) remain conflicting (2).
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