Abstract
Summary A statistical analysis of the results of a comparison of 4 measures of the thiacetazone sensitivity of 90 wild strains of the tubercle bacillus leads to the conclusion that the best measure is the drug concentration that inhibits growth of 20 colonies from a standard inoculum (MIC 20) after 28 days' incubation. There was no evidence of natural thiacetazone resistance among 30 British and 30 Sudanese strains; a few of the East African strains were apparently resistant to thiacetazone.
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