Abstract
The thermal phase behavior of the mono- and di- N-methylated derivatives of DPPE has been investigated by DSC and infrared spectroscopy. It is shown that these partially N-methylated DPPE derivatives present endothermic phase transitions at 48.2 and 58.0°C. The thermodynamic properties of these gel to liquid-crystalline transitions are comparable to those of DPPE and DPPC with no evidence for a pretransition in either of these N-methylated lipids. The progressive methyl substitution of the ethanolamine group of DPPE does not have a constant effect on reducing the transition temperature. The spectral properties of the gel phases of DPPE, DPMePE, DPMe 2PE and DPPC (or DPMe 3PE), suggest that there is a progressive increase in the acyl chain tilt angle from DPPE to DPPC, probably induced by the differences in the cross-sectional area of the headgroups which lead to small differences in the glycerol moiety.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
