Abstract

 Abstract
 
 Background: Oral cryotherapy has been scientifically proven as a non-pharmacological therapy to reduce the incidence of oral mucositis. With the decline in the incidence of oral mucositis, patient’s comfort improved, the length of stay and cost of care decreases, and maximum quality of life is achieved. Aim: To determine the effectiveness of oral cryotherapy in reducing the incidence of oral mucositis in patient undergoing chemotherapy. Method: This paper used literature review. The literature search was conducted of articles published from January 2012 through February 2018 using the PubMed, Embase, Cochrane Library and Ebscohost databases on the effectiveness of oral cryotherapy in reducing oral mucositis in patients undergoing chemotherapy. Result: This search resulted in a total of 8 articles. Evidence has indicated that there is a significance effect of oral cryotherapy in reducing oral mucositis. Conclusion: Oral cryotherapy is one of technique that easy to do, inexpensive and can be tolerated by patients in general, so it can be used widely. It can be used for adults and children with solid tumors, bone marrow transplant patients and for patients with different chemotherapy regimens (single or combination regimens).
 
 
 Keywords: Oral Cryotherapy, Oral Mucositis, Chemotherapy, patient’s quality of life
Highlights
Cancer is one of the leading causes of death worldwide
The result of the present study reveals that there was highly significant decrease in the occurrence of oral mucositis observed in the children treated with flavored ice cubes than plain ice cubes at p
Oral cryotherapy is one of the non-pharmacological actions useful for reducing the incidence and severity of oral mucositis in cancer patients undergoing chemotherapy. This technique is easy to do, inexpensive and can be tolerated by patients in general, so it can be used widely. It can be used for adults and children with solid tumors, bone marrow transplant patients and for patients with different chemotherapy regimens
Summary
Cancer is one of the leading causes of death worldwide. Cancer is the second leading cause of death globally and is estimated to account for 9.6 million deaths in 2018 [1]. The increase of cancer cases is caused by several factors, including population growth, aging process, and a change in the prevalence of certain cancer causes associated with socio-economic development. More than 30% of death is caused by five behavioral and dietary factors, namely high body mass index, lack of fruit and vegetable intake, lack of physical activity, cigarette, and excessive alcohol consumption. The prevalence of NPC in Indonesia based on histopathology is reported to be around 6.2 cases for every 100,000 population each year [3]. The cause of NPC is strongly associated with Epstein-Barr virus (EBV) [4]
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