Abstract
Note.— This article and the articles in the previous issues ofThe Journalare part of a series published under the auspices of the Council on Pharmacy and Chemistry. Other articles will appear in succeeding issues. When completed, the series will be published in book form.—Ed. The testicle exercises at least two biologic functions of utility in the organism, the primary of which is maturation of germ cells and the secondary the secretion of one or more substances known as the testis hormone. The primary function is much the older and is exercised not only in vertebrates but in invertebrates as well. Hormone secretion, however, appears to be restricted to the vertebrates and to have undergone a gradual increase in complexity; it is on the accessory organs of reproduction that the influence of the testicular hormone is exercised. In some lower fish the sex cells are merely liberated from the gonad
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