Abstract
Various amide derivatives of o -chlorocinnamic acid, p -nitrocinnamic acid, and cinnamic acid were prepared and tested for antifungal activity against four organisms. N-(4-Chlorophenyl)-2-chlorocinnamamide proved to be the most active compound against M. gypseum and T. rubrum , while N-(3-chlorophenyl) cinnamamide proved to be the most active compound against M. canis and T. mentagrophytes . In general, the results of the test indicated that most of the cinnamamide derivatives had little or no antifungal activity in vitro .
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More From: Journal of Pharmaceutical Sciences (Scientific Edition)
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