Abstract
AbstractThe purpose of this research experiment was to perform and improve the synthesis of resveratrol (CAS: 501-36-0). Resveratrol (trans-3,4',5-trihydroxystilbene), a natural polyphenolic, non-flavonoid antioxidant, is a phytoalexin found naturally in many plants. The compound was synthesized using the decarbonylative Heck reaction. The modified four-step reaction generated poor yields but the spectra indicate that the overall resveratrol compound was obtained. Several improvements were made to help increase yield.
Highlights
For many past centuries man has been in search of an elixir
Resveratrol has been able to extend the life of Saccharomyces cerevisiae,6 Caenorhabditis elegans, Drosophila melanogaster, 7 and the mammal
The second trial had a more accurate melting point that ranged from 89-‐95 °C
Summary
In Partial Fulfillment of the Requirements for the Degree of BACHELOR OF SCIENCE. iii Figure 17: The IR of Resveratrol Triacetate, product of step 3.
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