Abstract

SK&F 97426A (10), a 1% crosslinked 11-trimethylammonioundecylmethacrylate chloride ethylene glycol dimethacrylate co-polymer bile acid sequestrant, has been prepared in two carbon-14 labelled forms, namely in the 1-position of the undecyl side chain and the pendant N-methyl group. 11-Bromo[1-14C]undecyl methacrylate has been prepared and conditions developed for its small scale suspension polymerisation.

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