The Synthesis and Physicochemical and Supramolecular Properties of Strained Phenylacetylene Macrocycles

Abstract

Strained phenylacetylene macrocycles, cyclic [3]- and [4]metaphenylacetylenes ([n]CMPAs) and methoxy derivatives, and cyclic [5]- to [9]paraphenylacetylenes ([n]CPPAs) were prepared using a strategy based on the McMurry coupling reaction. The physicochemical and supramolecular properties of these substances were determined. Interestingly, apart from [3]CMPAs, compounds in these series possess preorganized three-dimensional cavities. 1 Introduction 2 Theoretical Optimized Structures 3 Synthesis 4 Properties and Structures of Cyclic Metaphenylacetylenes 5 Properties and Structures of Carbon Nanorings 6 Outlook