Abstract

A new series of 4-{4-[(hydrazinylmethoxy)(hydroxy)methyl]phenyl}-3-methyl-3,4dihydro quinoxalin -2(1H)-one were designed and synthesized in order to evaluate their anti-tb activity. The structure of the synthesized compounds was confirmed by elemental analysis and spectral data (IR, 1H NMR and Mass). The data obtained from biological screening revealed that; synthesized compounds showed the good to moderate anti-tb activities.
 Keywords: Quinoxaline, ortho-phenylenediamine and hydrazinehydrate.

Highlights

  • Heterocycles compounds are used in many various industries[1]

  • The structure of the synthesized compounds was confirmed by elemental analysis and spectral data (IR, 1H NMR and Mass)

  • The data obtained from biological screening revealed that; synthesized compounds showed the good to moderate anti-tb activities

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Summary

Introduction

Heterocycles compounds are used in many various industries[1]. most of hetero cycle compounds aren’t extracted from nature source, but are synthesized. ABSTRACT: A new series of 4-{4-[(hydrazinylmethoxy)(hydroxy)methyl]phenyl}-3-methyl-3,4dihydro quinoxalin -2(1H)-one were designed and synthesized in order to evaluate their anti-tb activity. The data obtained from biological screening revealed that; synthesized compounds showed the good to moderate anti-tb activities.

Results
Conclusion

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