Abstract
In the current study, injured peripheral nerves were treated with a regular treadmill exercise program in combination with a nanofibrous neural channels loaded with arctium lappa extract (ALE). In Vitro studies showed that the neural channels were biocompatible and potentially facilitated gas exchange through the scaffolds. In addition, the produced scaffolds modulated the inflammatory responses. In Vivo study showed that the animals treated with both exercise and neural channels had the highest rate of functional recovery and histopathological restorations.
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