Abstract
The study aimed to compare the chemical composition and in vitro antioxidant activity of an extract obtained from Cannabis sativa L and golden root (Rhodiola rosea L), which are both used as natural anxiolytics. The phytochemical profile (HPLC - DAD analysis), total polyphenol content (TPC), and antioxidant capacity (AOC) of the combination of Rhodiola rosea extract and Cannabis sativa oil were investigated to study their effects. To determine the DPPH radicalscavenging activity, an electron paramagnetic radical spectrometer (EPR-X-band) was used as a promising technique. The results indicated that the new extract derived from the combination of Rhodiola rosea and Cannabis sativa was richer in phenolic compounds and exhibited higher antioxidant activity. These findings provide valuable insights for potential in vivo studies that involve the simultaneous use of the two plants.
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