Abstract
Glossina austeni can readily be infected with T. brucei (Lugala I), by using guinea-pigs as donor and recipient hosts and lop-eared rabbits as maintenance hosts. The age of the fly at the time of the infective meal is the most important factor in successful laboratory infections. Flies 1 day old had a midgut infection rate of 27%, but less than 1% of older flies became infected. 3% of flies 1 day old developed salivary gland infections. A complete cyclical transmission of T. brucei was demonstrated. The infection procedures have been performed often enough to indicate that this system should be a useful model for the study of African trypanosomiasis.
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