Abstract
The suffering associated with syphilitic visceral crises, inoperable carcinomas with metastases, angina pectoris, and trigeminal neuralgia needs only to be mentioned to emphasize that there are many unsolved problems associated with the physiology of pain and the surgical procedures employed for its relief. Certain clinical and experimental observations are of interest in an attempt to learn more of the pathways for the conduction of painful impulses and the methods employed for their surgical relief. In many instances, surgical empiricism has preceded known anatomic and physiologic facts in attempts to relieve the pain of some of these diseases. Some years ago, Ranson and his associates1found in the cat that, as the posterior spinal roots enter the spinal cord, there is a sharp separation of the larger myelinated from the finest myelinated and unmyelinated fibers. The latter fibers, which constitute the lateral division of the root, are so placed that
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