Abstract
Background The surgical treatment of patients affected by BRONJ (Bisphosphonate-related osteonecrosis of the jaw) represents one of the most debated issues in the international literature becouse the data reported to date are preliminary results of long-term studies. In accordance with the guidelines proposed in 2007 by the American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-Related Osteonecrosis of the Jaws and confirmed by the Update 2009 of the same document, surgical treatment should be reserved only to cases of BRONJ in an advanced stage (Stage III) or in the presence of a well-defined bone sequestration. Unfortunately the proposed classification, even if very schematic and user-friendly, in our opinion is still too rigid and does not take into account the patient as a whole.
Highlights
The surgical treatment of patients affected by BRONJ (Bisphosphonate-related osteonecrosis of the jaw) represents one of the most debated issues in the international literature becouse the data reported to date are preliminary results of long-term studies
Materials and methods At the University Hospital of Parma, a study group has been formed since 2005 for the treatment of patients with BRONJ, involving the various specialties involved in the management of this disease
In our patients with BRONJ encouraging results have been achieved by surgical therapy performed early, bringing valuable clinical success over 80% of treated sites, compared with results obtained with medical therapy alone
Summary
The surgical treatment of patients affected by BRONJ (Bisphosphonate-related osteonecrosis of the jaw) represents one of the most debated issues in the international literature becouse the data reported to date are preliminary results of long-term studies. In accordance with the guidelines proposed in 2007 by the American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-Related Osteonecrosis of the Jaws “ and confirmed by the Update 2009 of the same document, surgical treatment should be reserved only to cases of BRONJ in an advanced stage (Stage III) or in the presence of a well-defined bone sequestration. The proposed classification, even if very schematic and user-friendly, in our opinion is still too rigid and does not take into account the patient as a whole
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