Abstract
Neonatologists often are criticized because of the empiric nature of our specialty and our past history of iatrogenic disasters. Very few, if any, current therapies have been proven to be of value by the "gold standard" evidence of large, randomized control trials. Now, at long last, we seem to have gotten it right. The most exciting new therapy in decades, surfactant replacement therapy, has been introduced into neonatal care, and it has been done correctly. It's taken nearly 40 years to advance from basic research, animal studies, small human pilot studies, to the final stage of gold standard evidence from more than 33 randomized trials involving thousands of low birth weight infants.
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