Abstract

The purpose of the present work was to study the characteristics of the cell coat in embryonic cells programmed to die. Interdigital mesenchymal cells of the chick embryo hind limb were studied prior to and during their spontaneous degeneration after ruthenium red, conA-peroxidase and conA-ferritin labelling. No significant cell coat differences were observed in healthy mesenchymal cells one day before the degenerative process and during its commencement. Also dying cells had a conspicuous coat. Only cells in advanced stages of degeneration showed conspicuous cell coat alterations. The results are discussed with respect to the mechanism of spontaneous degeneration and subsequent phagocytosis of the dying cells.

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