Abstract
In 91 male rats, silver or platinum coils were Implanted into the vasa deferentia with the hope of developing a simple and reversible method for male fertility control. The insertion of the coil by inguinal incision promises a high success rate, and side effects such as sperm granuloma, device extravasation, displacement of the testes, and artificial ascensus could be prevented. In an in vitro experiment simulating the vas deferens anatomical conditions, the immobilizing capacity of the device was evident, and the motility of the spermatozoa decreased to 0% within 30 minutes. Longterm in vivo experiments showed no changes in the reproductive organs. However, the high rate of pregnancy after placement of the device (55%) does not suggest that such devices could offer a practical method of achieving male sterility.
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