The Successful Resuscitation in a Neonate with Down Syndrome after 45 minutes: A Case Report

Mahin Seyedhejazi,Haleh Farzin,Nasrin Taghizadieh,Maryam Haghighat Azari

doi:10.7575/aiac.abcmed.v.9n.2p.34

Abstract

Introduction: Patients with Down syndrome (DS due to relative macroglossia and dynamic airway collapse) are vulnerable to significant upper airway complications. Obstructive sleep apnea (OSA) is a common condition and noted in about 79% of these children . Children with OSA, with or without DS, are sensitive to respiratory depression by drugs such as sedatives, opioids and hypnotics. Abnormalities of the cardiovascular system are also common in Down syndrome. Case Report: A nine_ day old male preterm newborn with DS (e.g. gestational age of 35 weeks) was brought to operation room (OR) for insertion of central venous line and surgery of duodenal atresia. During transportation to NICU, in OR he arrested and then after 45 minutes resuscitation, he returned to life. Conclusion: The placement of CVL could precipitate triggers of cardiac arrest, particularly in preterm newborn.

Highlights

Patients with Down syndrome (DS due to relative macroglossia and dynamic airway collapse) are vulnerable to significant upper airway complications
Down syndrome(DS) is one of most prevalent congenital abnormalities[1].It is most obviously that outcome is poor in resuscitation cases due to cardiac or cardiorespiratory arrest, and is associated with 87% to 89% mortality rate or sever morbidity[2]
Children with heart disease in comparison with patients without heart disease may be sicker in the time of occurrence of anesthesia – related cardiac events and they experience higher mortality rate. These types of arrests are frequently reported from general operation room and it has probably originated from cardiovascular reasons [3]

Summary

Introduction

Patients with Down syndrome (DS due to relative macroglossia and dynamic airway collapse) are vulnerable to significant upper airway complications. Obstructive sleep apnea (OSA) is a common condition and noted in about 79% of these children. Children with OSA, with or without DS, are sensitive to respiratory depression by drugs such as sedatives, opioids and hypnotics. Abnormalities of the cardiovascular system are common in Down syndrome. Case Report: A nine_ day old male preterm newborn with DS (e.g. gestational age of 35 weeks) was brought to operation room (OR) for insertion of central venous line and surgery of duodenal atresia. During transportation to NICU, in OR he arrested and after 45 minutes resuscitation, he returned to life. Conclusion: The placement of CVL could precipitate triggers of cardiac arrest, in preterm newborn

INTRODUCTION

Findings

CONCLUSION