Abstract
The Tc(V)-99m Dimercaptosuccinate (DMS) as a tumor seeking agent has been studied by several laboratories. The published preparation methods were either in situ complexation or two step constitution of commercial renal imaging kit. A new formulation of lyophilized instant kit for one step preparation of Tc(V)-99m DMS complex has been developed in this study. High labeling yield (over 95%) and good shelf stability of the kit were obtained in our laboratory by investigating the formulation of Tc-99m complexes with radio-TLC, electrophoresis and HPLC methods. The results of clinical trial showed the superiority of scintigraphy for diagnosis of bone tumors, soft-tissue tumors and their malignant metastases.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
