Abstract

Only one group was investigated for serum lipid profile in third trimester of pregnancy in which included all PIH patients admitted in labor room in Department of Obstetrics in Jhalawar Medical College and was substantially compared with the normal values of Lipids in women. In this study we investigate the role of lipid profile in PIH. LDL value increase, HDL value decrease, TG value increase and VLDL value increase in PIH patients and also TG : HDL ration increased significantly in PIH patients. Dyslipidemia mediated activation of endothelial cells to placentally derived endothelial disturbing factors like lipid peroxides and trophoblastic components as possible contributors for pathogenesis of PIH. Thus assessment of blood lipids may be helpful in preventions of complications in PIH.
 Key Words: Bloodlipids, PIH, Dyslipidemia, Triglycerides, Low Density Lipoprotiens, High Density Lipoprotiens.

Highlights

  • Pre-eclampsia, a non cancel convulsive form of pregnancy induced hypertension accounts for a significant proportion of maternal and fetal morbidity and mortality[1]

  • The risk of developing eclampsia appears to be greater in women who have family history of essential hypertension and their may be a relationship between risk of preeclampsia and the metabolic syndrome[2]

  • The data were intended in Ms Excel and we find out the mean and SD of lipid profile in Pregnancy Induced Hypertension (PIH) patients and we show that: Table 3: Mean and SD of lipid profile in PIH patients

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Summary

Introduction

Pre-eclampsia, a non cancel convulsive form of pregnancy induced hypertension accounts for a significant proportion of maternal and fetal morbidity and mortality[1]. Over 100,000 women develop eclampsia per year. The risk of developing eclampsia appears to be greater in women who have family history of essential hypertension and their may be a relationship between risk of preeclampsia and the metabolic syndrome[2]. Pre-eclampsia when complicated with convulsion is called eclampsia. The disorder complicates approximately 5 to 7 percent of pregnancies[3,4,5]. Severe PIH is associated with substantial risk for the foetus these include intrauterine growth restriction death and prematurity with attendant complications where as the mother is at risk of renal failure, pulmonary edema, stroke and death.

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